Polysorbate 80
Polysorbate 80

Polysorbate 80

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CAS: 9005-65-6

INCI: Polysorbate 80

Chemical Structure:

  • Polysorbate 80 is a non-ionic surfactant and emulsifier. It is derived from sorbitol and oleic acid and belongs to the polysorbate family.

Physical Form:

  • Polysorbate 80 is typically found as a clear to yellowish liquid.

Function and Uses:

  1. Emulsifier: Polysorbate 80 is widely used as an emulsifier in various cosmetic and pharmaceutical products. It helps stabilize emulsions, allowing oil and water-based ingredients to remain well-dispersed.

  2. Surfactant: As a surfactant, polysorbate 80 lowers the surface tension between different substances, facilitating the mixing of oil and water.

  3. Solubilizer: It is commonly employed to solubilize or dissolve hydrophobic substances, such as essential oils, in water-based formulations.

  4. Stabilizer: Polysorbate 80 contributes to the stability of formulations, preventing the separation of ingredients and ensuring uniform distribution.

  5. Wetting Agent: It is used as a wetting agent in certain formulations to improve the spreading and wetting of surfaces.

Common Applications:

  • Polysorbate 80 is found in a wide range of products, including skincare and hair care formulations, pharmaceuticals, food products, and industrial applications.


  1. Improved Emulsion Stability: Polysorbate 80 enhances the stability of emulsions, preventing the separation of oil and water phases in formulations.

  2. Solubilization of Hydrophobic Ingredients: Its solubilizing properties make it effective in incorporating hydrophobic ingredients into water-based formulations, improving overall product performance.

  3. Enhanced Skin Penetration: Polysorbate 80 is sometimes used to enhance the skin penetration of certain ingredients in skincare formulations.

  4. Mild and Non-Irritating: Generally considered mild, it is suitable for a variety of personal care applications.


  • Polysorbate 80 is generally regarded as safe for use in cosmetic and pharmaceutical products. However, individuals with known sensitivities should always check product labels and perform patch tests if necessary.

Regulatory Status:

  • Polysorbate 80 is widely accepted and considered safe for use in cosmetics, pharmaceuticals, and food products when formulated according to regulatory guidelines.

Usage Instructions:

  • Manufacturers incorporate polysorbate 80 into formulations at recommended concentrations to achieve the desired emulsifying, solubilizing, and stabilizing effects.
  • Specific usage guidelines may vary depending on the product type and formulation requirements.

Certificate of Analysis - Material Safety Data Sheet

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